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We'll hear conversations from Appalachia — the mountain region that stretches from New York to the Deep South. This remains a region where incomes lag well behind the national average.

President Andrew Jackson, who is the face of the $20, will be replaced by abolitionist leader Harriet Tubman. Lourdes Garcia-Navarro talks to Susan Ades Stone, co-founder of the group Women On $20s.

A federal appeals court ruled a transgender boy may sue the school board for discrimination because it banned him from using the boy's bathroom. Attorney Joshua Block talks to Lourdes Garcia Navarro.

On this week's episode of Out and About, Dr. Mae Gilliland of ArtsPartners of Central Illinois talks to Sharon Samuels Reed, founder and artistic director of The Heritage Ensemble. Sharon reflects on founding the Ensemble and the mission that continues to guide its work.

Scientists are trying to decode how the trillions of microorganisms in our gut talk with the brain and shape our resilience to stress. A new study offers some initial clues.

Wilmer Vasquez died at just 29 years old after suffering heat illness during the hottest year on record. His brother, Yonatan, says climate change played a big role.

In Brazil, year-round epidemics of what is known as “breakbone fever” are becoming the norm, weighing heavily on healthcare systems and pushing leaders to look for new solutions to combat the disease.

NPR’s Ari Shapiro speaks with musician and composer Ameen Mokdad, about his album The Curve, which he composed while living under ISIS occupation in Mosul, Iraq.

President Biden’s executive moves to severely limit asylum for those entering the U.S. without authorization are being met in immigrant communities with a mix of confusion, angst and disappointment.

For the first time in U.S. history, the federal government is trying to count most households through the Internet for the once-a-decade census, but the rollout has been fraught with risks.