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Merck and Moderna announced a successful late-stage trial for a melanoma vaccine. NPR's Leila Fadel talks to Dr. Robert Vonderheide of Penn Medicine and the American Association for Cancer Research.

It's Sept. 25, and in a nod to "9 to 5," people in Nashville, Tenn., and other places are celebrating the Queen of Country, Dolly Parton.

Metro Phoenix has so far seen twice as many heat deaths as this time last year. Authorities are trying to understand why and how to intervene.

The USDA's flagship agricultural research lab could close this week. Scientists warn that could hurt U.S. food supply.

Thousands of unaccompanied immigrant children are set to lose legal representation. The federal contract that pays for legal access expired Friday.

Americans are abandoning their long-trusted news outlets in high numbers. According to a Pew Research Center report, 31 percent of Americans say they have deserted a particular news outlet because it no longer provides the information they want.

Legal expert Jeffrey Rosen says of the Supreme Court nominee: "If he thought that individual liberty was threatened by presidential or congressional overreaching, then he would step in."

The federal government shutdown continues. Republicans and Democrats appear no closer to an agreement to end it. Many federal workers are missing full paychecks and don't know when they will resume.

In his new novel, The Plot Against America, Philp Roth imagines a 1940's fascist America led by flying ace and staunch isolationist Charles Lindbergh. NPR's Robert Siegel talks to Roth about his invented history.

Federal prisons saw a significant rise in deaths during the pandemic years, NPR found. Of those who died from COVID-19, nearly all were elderly or had health conditions, and many had tried to get out.