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For decades, scientists have searched for plants containing disease-fighting compounds. Some powerful cancer drugs are derived from a flower that grows in the forests of Madagascar. But experts say the oceans, teeming with life, might be a better place to search. As NPR's Eric Niiler reports, researchers are now scouring the seven seas in hopes of finding the next blockbuster drug.

NPR's Bob Edwards speaks to Mathea Falco, president of Drug Strategies, a non-profit, drug policy research institute, about faith-based and other drug treatment programs. President Bush has proposed to significantly increase drug treatment funding.

Troubleshooters are expected to scrutinize the shuttle Columbia's auxiliary power units, which help provide power to the orbiter's steering mechanisms during descent -- a task that requires highly flammable fuel. NPR's Howard Berkes joins host Steve Inskeep to talk about the role APUs play in reentry and why their redesign had been on NASA's to-do list. (This is a repeat from earlier in the show.)

Lt. Col. Dan Biggie, an Air Force chaplain, joins host Steve Inskeep from Cocoa Beach, Fla., where spectators had been waiting for the shuttle Columbia to land. He discusses the role of chaplains and how astronauts deal with the danger of their occupation. (This is a repeat from earlier in the show.)

Florida Senator Bill Nelson flew on the last shuttle mission before the 1986 Challenger explosion and joins host Steve Inkseep to share his perspective as a former astronaut and Floridian.

Talk of the Nation/Science Friday host Ira Flatow joins host Steve Inskeep to talk about how NASA has adapted since the 1986 Challenger disaster.

NPR's Jackie Northam reports on the disaster's impact on America's contribution to the international space station. (This is a repeat from earlier in the show.)

Host Steve Inskeep reviews what is known so far about the Columbia disaster.

Today President Bush was called upon for the second time to comfort a nation in mourning. He telephoned the families of the lost astronauts and then addressed the nation from the cabinet room. (This is a repeat from earlier in the show.)

NPR's Andy Bowers reports from Palmdale, Calif., where the space shuttle Columbia was upgraded in 2001. Palmdale is near Edwards Air Force Base, which was the original landing site during the space shuttle program's infancy. It is still the alternate landing site.