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If a Democrat wins an Ohio special election, it would be the latest sign of alarm for Republicans ahead of November's midterm election. Progressives hope for more upset wins Tuesday night.

NPR's Scott Simon speaks with author Aimen Dean about his time with al-Qaida in his new memoir, Nine Lives, My Time as the West's Top Spy Inside al-Qaeda.

In politics, trade means manufacturing, and manufacturing means America — a very particular, nostalgia-laden version of America.

It took decades, but John Coster-Mullen has pieced together specs for America's first nuclear bombs. Some believe his odyssey says something about North Korea's rapid nuclear progress.

The White House has been strong against China in trade talks, but NPR and PBS Frontline found top advisers battled for more than a year over imposing billions of dollars in tariffs on Chinese imports.

Six months after electing a diverse wave of women to Congress, "electability"-minded Democrats fear the country isn't ready for a woman, person of color or LGBTQ presidential candidate.

The explosion in online holiday shopping means billions of packages need to be delivered — and companies like UPS, FedEx and Amazon are under more pressure than ever.

Around 20% of U.S. adults live with chronic pain. Medical schools traditionally haven't dedicated much time to teaching about pain and pain control, but one top school now has a mandatory course.

Here are three big-picture takeaways after the Senate Judiciary Committee's release of more than 2,500 pages of transcripts, emails and other materials.

Lightfoot is the city's first black female and openly gay mayor. After her swearing in, she laid out a plan to make Chicago "a city that families want to move to, not run away from."