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When abiding fear takes over some kids' lives, they respond with anger and aggression that's not premeditated. One psychiatrist says he's finding profound relief for a particular subgroup of these children in experimental research with the anesthesia drug ketamine.

The Texas senator says giving a path to citizenship to immigrants in the U.S. illegally would be unfair to immigrants who followed the rules, like his own father, 74-year-old Rafael Bienvenido Cruz. He portrays his dad as a kind of Cuban Horatio Alger.

Researchers say that they've discovered a new subatomic particle - one that appears to contain four quarks bound together. Physicist Sean M. Carroll describes the significance of the find, and talks about the ongoing effort in physics to explain why the universe is the way it is.

What happens when you ask architects to re-imagine a structure mandated by the Jewish holy book? A freaking cool cultural piece of art, that's what.

Residents of the St. Louis area don't all agree on which politicians to blame for the government shutdown, but they do agree that they're doing a lousy job and should have their pay suspended.

The chief engineer of the MV Seaman Guard Ohio, one of 35 arrested for allegedly carrying illegal weapons, was reportedly prevented by cellmates from killing himself.

Iran and six world powers have set a July 20 deadline for reaching a deal on Iran's nuclear program. With the clock ticking, here's a look at the main obstacles.

While workers scramble to prepare stadiums and airports for visiting fans, NPR's Lourdes Garcia-Navarro says many Brazilians are angry and frustrated.

Author Michael Lewis says high-frequency traders have figured out a way to game the system. Some of those traders say that while there are "bad actors," high-speed trading plays a legitimate role.

The fashion guru plays our game, and makes us feel a little better about our pleated pants. Originally broadcast June 6, 2014.